Phospho-MLKL (S358) Antibody - Cat. #: CSB-RA850851A358phHU

SKU: CSB-RA850851A358phHU

Size :50ul

Clone Number:4A6

Aliases:Mixed lineage kinase domain-like protein, hMLKL, MLKL

Product Type:Recombinant Antibody

Immunogen Species:Human

UniProt ID:Q8NB16

Immunogen:A synthesized peptide derived from human Phospho-MLKL (S358)

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:50-1:200

Background:Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MLKL

Research Areas:Signal Transduction