Phospho-MDM4 (Ser367) Antibody - Cat. #: CSB-PA975669

SKU: CSB-PA975669

Size :100ul

Clone Number:

Aliases:DKFZp781B1423 antibody; Double minute 4 antibody; Double minute 4 human homolog of p53 binding protein antibody; Double minute 4 protein antibody; HDMX antibody; MDM 4 antibody; Mdm2 like p53 binding protein antibody; Mdm2-like p53-binding protein antibody; MDM4 antibody; Mdm4 p53 binding protein homolog mouse antibody; Mdm4 protein antibody; MDM4 related protein 1 antibody; Mdm4 transformed 3T3 cell double minute 4 antibody; Mdm4 transformed 3T3 cell double minute 4 p53 binding protein antibody; Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse antibody; MDM4_HUMAN antibody; Mdmx protein antibody; MGC132766 antibody; Mouse double minute 4 homolog antibody; Mouse double minute 4 human homolog of p53 binding protein antibody; MRP 1 antibody; MRP1 antibody; p53 binding protein antibody; p53 BINDING PROTEIN MDM4 antibody; p53-binding protein Mdm4 antibody; Protein Mdm4 antibody; Protein Mdmx antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15151

Immunogen:Peptide sequence around phosphorylation site of serine 367 (T-I-S(p)-A-P) derived from Human MDM4.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MDM4

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism