Phospho-MDC1 (Ser513) Antibody - Cat. #: CSB-PA052744

SKU: CSB-PA052744

Size :100ul

Clone Number:

Aliases:Homologue to Drosophila photoreceptor protein calphotin antibody; MDC 1 antibody; Mdc1 antibody; MDC1_HUMAN antibody; Mediation of DNA damage checkpoint 1 antibody; Mediator of DNA damage checkpoint 1 antibody; Mediator of DNA damage checkpoint protein 1 antibody; NFBD 1 antibody; NFBD1 antibody; Nuclear factor with BRCT domains 1 antibody; Nuclear Factor with BRCT Domains Protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14676

Immunogen:Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:

The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

Nagase T., DNA Res. 3:17-24(1996).
Shiina T., Genetics 173:1555-1570(2006).
Mungall A.J., Nature 425:805-811(2003).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MDC1

Research Areas:Epigenetics and Nuclear Signaling