Phospho-IRS1 (Ser636) Polyclonal Antibody

SKU: E-AB-20908

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: IRS-1 (phospho Ser636)

Target Synonym: HIRS 1;HIRS1;Insulin receptor substrate 1;IRS 1;IRS-1;IRS1;IRS1;OTTHUMP00000164234

Research Areas: Cancer;Cardiovascular;Metabolism;Neuroscience;Signal Transduction;Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P35568

Accession:

Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 132kDa

ObservedMW: 150kDa