Phospho-CXCR4 (Ser339) Polyclonal Antibody

SKU: E-AB-21282

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: Fusin (phospho Ser339)

Target Synonym: C-X-C chemokine receptor type 4;CD184;CD184 antigen;Chemokine (C X C motif) receptor 4;Chemokine CXC Motif Receptor 4;CXC-R4;CXCR-4;CXCR4;CXCR4;D2S201E;FB22;Fusin;HM89;HSY3RR;LAP 3;LAP3;LCR1;LESTR;Leukocyte derived seven transmembrane domain receptor;Leukocyte-derived seven transmembrane domain receptor;Lipopolysaccharide associated protein 3;Neuropeptide Y receptor Y3;NPY3R;NPYR;NPYRL;NPYY3;NPYY3R;Probable G protein coupled receptor lcr1 homolog;SDF 1 receptor;SDF-1 receptor;SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR;Stromal cell derived factor 1 receptor;Stromal cell-derived factor 1 receptor;WHIM;WHIMS

Research Areas: Cancer;Metabolism;Immunology;Microbiology;Neuroscience;Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat;Monkey

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P61073

Accession:

Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 40kDa

ObservedMW: 38kDa