Phospho-Bad (S91) Polyclonal Antibody

SKU: BT-PHS00725

Size:100μL

Background:The protein encoded by BAD (BCL2 associated agonist of cell death) is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of BAD results in two transcript variants which encode the same isoform.

Research_area:Cell Biology; Cancer

Target_protein:BAD

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, mouse, rat, monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Phospho-Bad (S91) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):18392

UniProt accession:Human: Q92934; Mouse: Q61337; Rat: O35147

Synonyms:BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter

GeneID:Human: 572; Mouse: 12015; Rat: 64639