Phospho-ATF1 (Ser63) Antibody - Cat. #: CSB-PA107926

SKU: CSB-PA107926

Size :100ul

Clone Number:

Aliases:Activating transcription factor 1 antibody; ATF 1 antibody; atf1 antibody; ATF1 EWS fusion gene antibody; ATF1 FUS fusion gene antibody; ATF1_HUMAN antibody; cAMP dependent transcription factor 1 antibody; cAMP-dependent transcription factor ATF-1 antibody; Cyclic AMP dependent transcription factor ATF 1 antibody; Cyclic AMP dependent transcription factor ATF1 antibody; Cyclic AMP-dependent transcription factor ATF-1 antibody; EWS AFT1 antibody; FUS ATF 1 antibody; FUS/ATF 1 antibody; Protein TREB36 antibody; RNA binding protein activating transcription factor 1 fusion protein antibody; TREB 36 antibody; TREB36 antibody; TREB36 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P18846

Immunogen:Peptide sequence around phosphorylation site of serine 63(R-P-S(p)-Y-R) derived from Human ATF1 .

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

Mackenzie KF, et al. (2013) J Immunol 190, 565-77
Dickinson RJ, et al. (2011) J Biol Chem 286, 38018-26
Wang J, Zhou JY, Wu GS (2011) J Biol Chem 286, 22384-92

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ATF1

Research Areas:Epigenetics and Nuclear Signaling