Phospho-ADRB2 (Ser346) Antibody - Cat. #: CSB-PA758017

SKU: CSB-PA758017

Size :100ul

Clone Number:

Aliases:ADRB2 antibody; ADRB2_HUMAN antibody; ADRB2R antibody; ADRBR antibody; Adrenergic beta 2 receptor surface antibody; Adrenoceptor beta 2 surface antibody; B2AR antibody; BAR antibody; beta 2 adrenoceptor antibody; Beta 2 adrenoreceptor antibody; Beta-2 adrenergic receptor antibody; Beta-2 adrenoceptor antibody; Beta-2 adrenoreceptor antibody; BETA2AR antibody; Catecholamine receptor antibody; OTTHUMP00000160386 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P07550

Immunogen:Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3
24690384 Curated Info
Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94
Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ADRB2

Research Areas:Cardiovascular;Signal transduction