PHF21A Antibody - Cat. #: CSB-PA017911LA01HU

SKU: CSB-PA017911LA01HU

Size :50ug

Clone Number:

Aliases:BHC80a antibody; BM-006 antibody; BRAF35-HDAC complex protein BHC80 antibody; BRAF35/HDAC2 complex (80 kDa) antibody; KIAA1696 antibody; PF21A_HUMAN antibody; PHD finger protein 21A antibody; PHF21A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96BD5

Immunogen:Recombinant Human PHD finger protein 21A protein (312-487AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background:Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of \\\'Lys-4\\\' of histone H3 in vitro, suggesting a role in demethylation regulation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PHF21A

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience