PDK3 Antibody - Cat. #: CSB-PA613585ESR2HU

SKU: CSB-PA613585ESR2HU

Size :50ul

Clone Number:

Aliases:[Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial antibody; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 antibody; CMTX6 antibody; GS1-358P8.4 antibody; mitochondrial antibody; PDK3 antibody; PDK3_HUMAN antibody; Pyruvate dehydrogenase kinase isoenzyme 3 antibody; Pyruvate dehydrogenase kinase isoform 3 antibody; Pyruvate dehydrogenase kinase isozyme 3 antibody; Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15120

Immunogen:Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (137-406AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PDK3

Research Areas:Metabolism; Signal transduction