PDGFRB Polyclonal Antibody

SKU: E-AB-32531

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PDGFR-β

Target Synonym: Beta platelet derived growth factor receptor;Beta-type platelet-derived growth factor receptor;CD 140B;CD140 antigen-like family member B;CD140b;CD140b antigen;IBGC4;IMF1;JTK12;OTTHUMP00000160528;PDGF R beta;PDGF-R-beta;PDGFR 1;PDGFR;PDGFR beta;PDGFR1;PDGFRB;PGFRB;Platelet derived growth factor receptor 1;Platelet derived growth factor receptor beta;Platelet derived growth factor receptor beta polypeptide

Research Areas: Cancer;Cardiovascular;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P09619

Accession:

Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human PDGFR-β around the non-phosphorylation site of Tyr751.

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 124kDa

ObservedMW: 124kDa