PAK Gamma Monoclonal Antibody

SKU: BT-MCA0984

Size:100μL

Background:The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Research_area:Signal transduction; Cancer; Cell biology; Microbiology

Target_protein:PAK2

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human,Monkey

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Serine,threonine-protein kinase PAK 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: Q13177; Mouse: Q8CIN4

Synonyms:PAK2; Serine; threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6; H4 kinase; p21-activated kinase 2; PAK-2; p58

GeneID:Human: 5062