PAIP1 antibody , Cat. # FNab06116

SKU: FNab06116

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain.

Immunogen:poly(A) binding protein interacting protein 1

Synonyms:

Observed MW:60 kDa,51 kDa,40 kDa

Uniprot ID:Q9H074

Reactivity:Human, Mouse, Rat, Monkey

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID:10605

Research Area:Metabolism