P4HB Monoclonal Antibody

SKU: BT-MCA3621

Size:100μL

Background:This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Research_area:Others

Target_protein:P4HB

applications:WB, IHC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:4E10C6

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:P4HB

Immunogen:Purified recombinant fragment of human P4HB (AA: 309-508) expressed in Mammalian.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):57.1kDa

UniProt accession:P07237

Synonyms:DSI,GIT,PDI,PHDB,PDIA1,PO4DB,PO4HB,PROHB,CLCRP1,ERBA2L,P4Hbeta

GeneID:5034