OSTCN rabbit pAb

SKU: ES11059

Size: 100μL

Source:Rabbit

Applications:WB IF;ELISA

Reactivity:Human;Rat;Mouse

Dilution:WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

Immunogen:Synthesized peptide derived from part region of human protein AA range: 31-80

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):11kD

Human_gene_id:632

Human_swiss_prot_no:P02818

Subcellular_location:Secreted.

Other_name:

Background:This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],