OAZ1 Antibody - Cat. #: CSB-PA016245DSR1HU

SKU: CSB-PA016245DSR1HU

Size :50ul

Clone Number:

Aliases:Antizyme 1 antibody; Antizyme antibody; AZI antibody; MGC138338 antibody; OAZ 1 antibody; OAZ antibody; OAZ1 antibody; OAZ1_HUMAN antibody; ODC Az antibody; ODC-Az antibody; Ornithine decarboxylase antizyme 1 antibody; Ornithine decarboxylase antizyme antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P54368

Immunogen:Recombinant Human Ornithine decarboxylase antizyme 1 protein (1-68AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake by binding to and targeting ODC1 for degradation (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OAZ1

Research Areas:Cancer; Metabolism; Signal transduction