NUMA1 Antibody - Cat. #: CSB-PA114858

SKU: CSB-PA114858

Size :100ul

Clone Number:

Aliases:Centrophilin stabilizes mitotic spindle in mitotic cells antibody; NMP 22 antibody; Nuclear matrix protein 22 antibody; Nuclear mitotic apparatus protein 1 antibody; Nuclear mitotic apparatus protein antibody; NUMA 1 antibody; NUMA antibody; NuMA protein antibody; NUMA1 antibody; NUMA1_HUMAN antibody; SP H antigen antibody; SP-H antigen antibody; Structural nuclear protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14980

Immunogen:Synthesized peptide derived from internal of Human NUMA1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.

Yang C.H., J. Cell Biol. 116:1303-1317(1992).
Compton D.A., J. Cell Biol. 116:1395-1408(1992).
Maekawa T., J. Cell Sci. 105:589-600(1993).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NUMA1

Research Areas:Cell biology