NRF-1 rabbit pAb

SKU: ES6416

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat;Bovine

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human NRF1. AA range:221-270

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):54kD

Human_gene_id:4899

Human_swiss_prot_no:Q16656

Subcellular_location:Nucleus.

Other_name:NRF1; Nuclear respiratory factor 1; NRF-1; Alpha palindromic-binding protein; Alpha-pal

Background:This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],