NR1H4 Antibody, HRP conjugated - Cat. #: CSB-PA839406LB01HU

SKU: CSB-PA839406LB01HU

Size :50ug

Clone Number:

Aliases:BAR antibody; Bile acid receptor antibody; Farnesoid X activated receptor antibody; Farnesoid X receptor antibody; Farnesoid X-activated receptor antibody; Farnesol receptor HRR 1 antibody; Farnesol receptor HRR-1 antibody; Farnesol receptor HRR1 antibody; FXR antibody; HRR 1 antibody; HRR1 antibody; NR1H4 antibody; NR1H4_HUMAN antibody; Nuclear receptor subfamily 1 group H member 4 antibody; Retinoid X receptor interacting protein 14 antibody; Retinoid X receptor-interacting protein 14 antibody; RIP 14 antibody; RIP14 antibody; RXR interacting protein 14 antibody; RXR-interacting protein 14 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96RI1

Immunogen:Recombinant Human Bile acid receptor protein (1-476AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NR1H4

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction