NOX4 antibody , Cat. # FNab05806

SKU: FNab05806

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation.

Immunogen:NADPH oxidase 4

Synonyms:Kidney oxidase 1, KOX, KOX 1, NADPH oxidase 4, NOX4, Renal NAD(P)H oxidase, RENOX

Observed MW:60 kDa

Uniprot ID:Q9NPH5

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP, IF, FC

Recommended dilution:WB: 1:200-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100

Gene ID:50507

Research Area:Metabolism