NOTCH3 Antibody, FITC conjugated - Cat. #: CSB-PA892153LC01HU

SKU: CSB-PA892153LC01HU

Size :50ug

Clone Number:

Aliases:CADASIL antibody; CASIL antibody; NOTC3_HUMAN antibody; Notch 3 antibody; Notch 3 intracellular domain antibody; Notch homolog 3 antibody; Notch3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UM47

Immunogen:Recombinant Human Neurogenic locus notch homolog protein 3 protein (1301-1496AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NOTCH3

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cardiovascular; Stem cells