NHP2 Polyclonal Antibody

SKU: E-AB-18904

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: NHP2

Target Synonym: DKCB2;FLJ20479;H/ACA ribonucleoprotein complex subunit 2;NHP2;NHP2 like protein;NHP2 ribonucleoprotein;NHP2 ribonucleoprotein homolog (yeast) 1;NHP2 ribonucleoprotein homolog;NHP2; S. cerevisiae; homolog of;NHP2;NHP2P;NOLA2;Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs);Nucleolar protein family A member 2;snoRNP protein NHP2

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NX24

Accession:

Background: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

Concentration: 0.96 mg/mL

Immunogen: Fusion protein of human NHP2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:300

Calculated MW: 17 kDa

ObservedMW: Refer to figures