NFX1 Polyclonal Antibody

SKU: BT-AP02229

Size:100μL

Background:MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes| two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants| each of which encodes a different isoform| have been identified.

Research_area:Cell biology; Epigenetics and nuclear signaling; Immunology

Target_protein:NFX1

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Transcriptional repressor NF-X1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q12986; Mouse: B1AY10

Synonyms:Transcriptional repressor NF-X1 ;EC 6.3.2.-;Nuclear transcription factor; X box-binding protein 1

GeneID:Human: 4799