NEFH Polyclonal Antibody

SKU: E-AB-70063

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:NEFH

Target Synonym:200 kDa neurofilament protein;CMT2CC;Nefh;Neurofilament heavy polypeptide 200kDa;Neurofilament heavy polypeptide;Neurofilament triplet H protein;NF H;NF-H;NFH;NFH

Research Areas:Cancer;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P19246,P16884

Accession:

Background:NEFH,also named as KIAA0845 and NFH,Belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton,and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L,M,and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE:NF-L,65-68kd; NF-M,145-160kd and NF-H,200-220kd. This antibody recognize NEFH only.

Concentration:0.54 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse NF200

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:117kDa

ObservedMW:200kDa