NEDD4 Rabbit Polyclonal Antibody

SKU: BT-AP11511

Size:100μL

Background:This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors| endocytic machinery components and the tumor suppressor PTEN.

Research_area:Cell biology; Epigenetics and nuclear signaling; Neuroscience

Target_protein:NEDD4

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NEDD4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):145090

UniProt accession:Human: P46934; Mouse: P46935; Rat: Q62940

Synonyms:NEDD4

GeneID:Human: 4734; Mouse: 17999; Rat: 25489