NBN Monoclonal Antibody

SKU: BT-MCA3273

Size:100μL

Background:Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:NBN

applications:WB, IHC, ICC, FCM

Reactivity:Human, Rat

Clonality:Monoclonal

Clone ID:7E4A2

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:NBN

Immunogen:Purified recombinant fragment of human NBN (AA: 467-615) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):85kDa

UniProt accession:O60934

Synonyms:ATV, NBS, P95, NBS1, AT-V1, AT-V2

GeneID:4683