NBK (phospho Ser35) rabbit pAb

SKU: ES7133

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:Synthesized phospho-peptide around the phosphorylation site of human NBK (phospho Ser35)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:638

Human_swiss_prot_no:Q13323

Subcellular_location:Endomembrane system; Single-pass membrane protein. Mitochondrion membrane ; Single-pass membrane protein . Around the nuclear envelope, and in cytoplasmic membranes.

Other_name:BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4

Background:The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011],