MYL2 rabbit pAb

SKU: ES8862

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:Synthesized peptide derived from human MYL2. at AA range: 91-140

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):18kD

Human_gene_id:4633

Human_swiss_prot_no:P10916

Subcellular_location:Cytoplasm, myofibril, sarcomere, A band .

Other_name:Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v)

Background:Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008],