MSX2 Antibody - Cat. #: CSB-PA030362

SKU: CSB-PA030362

Size :100ul

Clone Number:

Aliases:CRS 2 antibody; CRS2 antibody; FPP antibody; Homeo box msh like 2 antibody; Homeobox protein Hox-8 antibody; Homeobox protein MSX 2 antibody; Homeobox protein MSX-2 antibody; Homeobox protein MSX2 antibody; Hox 8 antibody; Hox8 antibody; MSH antibody; Msh homeo box 2 antibody; Msh homeo box homolog antibody; Msh homeo box homolog 2 antibody; Msh homeobox 2 antibody; Msh homeobox homolog 2 antibody; Msx 2 antibody; MSX2 antibody; MSX2_HUMAN antibody; Parietal foramina 1 antibody; PFM 1 antibody; PFM antibody; PFM1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35548

Immunogen:Synthesized peptide derived from Internal of Human MSX2.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.

Hodgkinson J.E., Biochim. Biophys. Acta 1174:11-16(1993).
Jabs E.W., Cell 75:443-450(1993).
Iimura T., DNA Seq. 8:87-92(1997).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MSX2

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer?Cardiovascular;Signal transduction