MSH2 Polyclonal Antibody

SKU: BT-AP05622

Size:100μL

Background:MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:MSH2

applications:IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MSH2 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):104743

UniProt accession:Human: P43246; Mouse: P43247; Rat: P54275

Synonyms:MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2

GeneID:Human: 4436; Mouse: 17685; Rat: 81709