MRPS35 Polyclonal Antibody

SKU: E-AB-52862

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MRPS35

Target Synonym:28S ribosomal protein S28;28S ribosomal protein S28;mitochondrial;28S ribosomal protein S35;28S ribosomal protein S35 mitochondrial precursor;28S ribosomal protein S35;mitochondrial;DKFZp762P093;HDCMD11P;MDS023;MGC104278;mitochondrial;Mitochondrial ribosomal protein S28;Mitochondrial ribosomal protein S35;MRP S28;MRP S35;MRP-S28;MRP-S35;MRPS 28;MRPS 35;MRPS28;MRPS35;OTTHUMP00000240420;OTTHUMP00000240422;OTTHUMP00000240424;PSEC0213;RT35;S28mt;S35mt

Research Areas:Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P82673

Accession:

Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. MRPS35 (Mitochondrial Ribosomal Protein S35) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.

Concentration:0.96 mg/mL

Immunogen:Fusion protein of human MRPS35

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:37 kDa

ObservedMW:Refer to figures