MRPS18C Antibody - Cat. #: CSB-PA566482

SKU: CSB-PA566482

Size :100ul

Clone Number:

Aliases:MRPS18C antibody; CGI-134 antibody; 28S ribosomal protein S18c antibody; mitochondrial antibody; MRP-S18-c antibody; Mrps18-c antibody; S18mt-c antibody; 28S ribosomal protein S18-1 antibody; mitochondrial antibody; MRP-S18-1 antibody; Mitochondrial small ribosomal subunit protein bS18c antibody; Mitochondrial small ribosomal subunit protein bS18m antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y3D5

Immunogen:Synthesized peptide derived from internal of Human MRPS18C.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.

Lai C.-H., Genome Res. 10:703-713(2000).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Koc E.C., J. Biol. Chem. 276:19363-19374(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MRPS18C

Research Areas:Epigenetics and Nuclear Signaling;Tags & Cell Markers