Mouse Tyrosine-protein phosphatase non-receptor type 11,PTPN11 ELISA KIT

SKU: E1051Mo

Size:96 Tests-1 Kit

Background:Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus (PubMed:14967142). Positively regulates MAPK signal transduction pathway (By similarity). Dephosphorylates GAB1, ARHGAP35 and EGFR (By similarity). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity (By similarity). Dephosphorylates CDC73 (By similarity). Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification (PubMed:29644115). {ECO:0000250|UniProtKB:Q06124, ECO:0000269|PubMed:14967142, ECO:0000269|PubMed:29644115}.

Research_area:

Applications:ELISA

Target_protein:Ptpn11

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.08ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Tyrosine-protein phosphatase non-receptor type 11

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35235

MASS(Da):68035

GeneID:19247

Synonyms:Ptpn11

Gene names:Ptpn11

Standard solution:24ng/ml