Mouse T-lymphocyte activation antigen CD86,CD86 ELISA KIT

SKU: E1268Mo

Size:96 Tests-1 Kit

Background:Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (PubMed:23241883). {ECO:0000269|PubMed:23241883}.

Research_area:

Applications:ELISA

Target_protein:Cd86

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:19.8pg/ml

Detection range:37.5-2400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:T-lymphocyte activation antigen CD86

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P42082

MASS(Da):34666

GeneID:12524

Synonyms:Cd86

Gene names:Cd86

Standard solution:4800pg/ml