Mouse Plasma Kallikrein/KLKB1 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ2107

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Klkb1

Specificity: Natural and recombinant mouse KLKB1

Background: Plasma kallikrein?is a?protein?that in humans is encoded by the?KLKB1?gene. It is mapped to 4q35.2. This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: Expression system for standard: NS0; Immunogen sequence: G20-A638

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Reference:

Uniprot ID: P26262

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 16621

Protein Name: Plasma kallikrein

Gene Full Name: kallikrein B, plasma 1

Synonyms: CD94; KLRD1; KP43; NK cell receptor