Mouse Leptin Receptor ELISA Kit PicoKine®

SKU: EK0440

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: LEPR

Specificity: Natural and recombinant mouse Leptin receptor

Background: Leptin receptor (or Obese receptor, OBR) is a single membrane-spanning receptor most related to the gp130 signal-transducing component of the IL-6 receptor, the G-CSF receptor, and the LIF receptor. OB-R mRNA is expressed not only in choroid plexus, but also in several other tissues, including hypothalamus. Leptin acts through the leptin receptor, a single-transmembrane domain receptor of the cytokine-receptor family. Leptin controls energy balance and food intake through the leptin receptor in the hypothalamus of the brain, which suggests that some polymorphisms of the leptin receptor gene (LEPR) might contribute to obesity or obesity-related diseases. Leptin is also involved in the regulation of blood pressure through the leptin receptor.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L22-G839

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Uniprot ID: P48356

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 16847

Protein Name: Leptin receptor

Gene Full Name: leptin receptor

Synonyms: CD295; DB; HuB219; LEP R; LEPR; leptin receptor; OB R; OB receptor; OBR