Mouse Interleukin 1 Receptor 2,IL1R2 ELISA KIT

SKU: E0844Mo

Size:96 Tests-1 Kit

Background:Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity). {ECO:0000250, ECO:0000269|PubMed:8332913, ECO:0000269|PubMed:9662436}.

Research_area:

Applications:ELISA

Target_protein:Il1r2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:2.51ng/L

Detection range:5-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 1 Receptor 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P27931

MASS(Da):45645

GeneID:16178

Synonyms:Il1r2 Il-1r2 Il1rb

Gene names:Il1r2

Standard solution:2400ng/L