Mouse Dickkopf-3, DKK3 ELISA Kit

SKU: E1212Mo

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Research_area:Stem Cells

Applications:ELISA

Target_protein:DKK3

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.02ng/ml

Detection range:0.5-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-3

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9QUN9

MASS(Da):38,388

GeneID:50781

Synonyms:Dickkopf-3;Dickkopf-related protein 3;DKK 3;DKK3;Dkk-3;mDkk-3

Gene names:DKK3

Standard solution:24ng/ml