Mouse CCL20/MIP-3 alpha ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0454

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: CCL20

Specificity: Natural and recombinant mouse CCL20/MIP-3 alpha

Background: Macrophage Inflammatory Protein 3alpha (MIP3alpha), also called Chemokine, cc motif, ligand 20 (CCL20). The MIP-3alpha/CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3alpha/CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin. And Alanine MIP-3alpha and Serine MIP-3alpha, the two forms of MIP3alpha, that differ by one amino acid at the predicted signal peptide cleavage site. Both of them were chemically synthesized and tested for biological activity. And both flu antigen plus IL-2-activated CD4 (+) and CD8 (+) T lymphoblasts and cord blood-derived dendritic cells responded to Ser and Ala MIP-3alpha.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A28-M97

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Uniprot ID: O89093

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 20297

Protein Name: C-C motif chemokine 20

Gene Full Name: C-C motif chemokine ligand 20

Synonyms: Beta chemokine exodus 1; C C motif chemokine 20; CC chemokine LARC; CCL20; CKb4; LARC; MIP 3 alpha; MIP 3a; MIP3A; MIP-3α; SCYA20; Small inducible cytokine A20; ST38