Mouse Caspase 14,CASP14 ELISA KIT

SKU: E0783Mo

Size:96 Tests-1 Kit

Background:Non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and is required for cornification (PubMed:18156206). Regulates maturation of the epidermis by proteolytically processing filaggrin (PubMed:21654840). In vitro is equally active on the synthetic caspase substrates WEHD-ACF and IETD-AFC. Involved in processing of prosaposin in the epidermis (PubMed:24872419). May be involved in retinal pigment epithelium cell barrier function (By similarity). {ECO:0000250|UniProtKB:P31944, ECO:0000269|PubMed:11175259, ECO:0000269|PubMed:17515931, ECO:0000269|PubMed:18156206, ECO:0000269|PubMed:21654840, ECO:0000269|PubMed:24872419}.

Research_area:

Applications:ELISA

Target_protein:Casp14

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.19ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Caspase 14

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O89094

MASS(Da):29458

GeneID:12365

Synonyms:Casp14

Gene names:Casp14

Standard solution:48ng/ml