Mouse Bone Morphogenetic Protein 5, BMP5 ELISA Kit

SKU: E0773Mo

Size:96 Tests-1 Kit

Background:Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis (PubMed:7958439, PubMed:29321139). Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation (By similarity).

Research_area:Cardiovascular; Signal Transduction; Cell Biology

Applications:ELISA

Target_protein:BMP5

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.58ng/L

Detection range:1-400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein 5

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P49003

MASS(Da):51,512

GeneID:12160

Synonyms:AU023399;BMP5;BMP-5;Bone morphogenetic protein 5;se

Gene names:Bmp5

Standard solution:480ng/L