Mouse Bile Salt Export Pump, ABCB11 ELISA Kit

SKU: E1883Mo

Size:96 Tests-1 Kit

Background:Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates to hepatic bile acids homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner (PubMed:14570929, PubMed:11172067, PubMed:23764895, PubMed:22619174, PubMed:19228692). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (By similarity). Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ABCB11

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:4.56ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Bile salt export pump

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9QY30

MASS(Da):146,749

GeneID:27413

Synonyms:ABC1;ABC16;ABCB11;ATP-binding cassette sub-family B member 11;Bile salt export pump;Bs;Bsep;Lit;Lith1;PFI;PFIC2;PGY;Sister of P-glycoprotein;SPGP

Gene names:Abcb11

Standard solution:2400ng/L