Mouse Autophagy Related Protein 12, ATG12 ELISA Kit

SKU: E2644Mo

Size:96 Tests-1 Kit

Background:Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. (Microbial infection) May act as a proviral factor. In association with ATG5, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection.

Research_area:Cell Biology; Cancer; Cardiovascular; Metabolism

Applications:ELISA

Target_protein:ATG12

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:4.12ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Autophagy related protein 12

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9CQY1

MASS(Da):15,207

GeneID:67526

Synonyms:4931423H11Rik;A330058M13Rik;Apg;Apg12l;APG12-like;ATG12;Atg12l;Autophagy-related protein 12;Ubiquitin-like protein ATG12;

Gene names:Atg12

Standard solution:1600ng/L