MMP3 Monoclonal Antibody

SKU: BT-MCA2825

Size:100μL

Background:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Research_area:Cardiovascular

Target_protein:MMP3

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4F10

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MMP3

Immunogen:Purified recombinant fragment of human MMP3 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):54kDa

UniProt accession:P08254

Synonyms:SL-1, STMY, STR1, CHDS6, MMP-3, STMY1

GeneID:4314