MME Antibody - Cat. #: CSB-PA985136

SKU: CSB-PA985136

Size :100ul

Clone Number:

Aliases:Atriopeptidase antibody; CALLA antibody; CD10 antibody; CD10 antigen antibody; Common acute lymphocytic leukemia antigen antibody; DKFZp686O16152 antibody; EC 3.4.24.11 antibody; Enkephalinase antibody; EPN antibody; Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody; Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody; Membrane metallo endopeptidase antibody; Membrane metallo endopeptidase variant 1 antibody; Membrane metallo endopeptidase variant 2 antibody; Membrane metalloendopeptidase antibody; Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody; Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody; Membrane metalloendopeptidase variant 1 antibody; Membrane metalloendopeptidase variant 2 antibody; MGC126681 antibody; MGC126707 antibody; MME antibody; NEP antibody; NEP_HUMAN antibody; Neprilysin antibody; neprilysin-390 antibody; neprilysin-411 antibody; Neutral endopeptidase 24.11 antibody; Neutral endopeptidase antibody; Neutral endopeptidase, membrane-associated antibody; SFE antibody; Skin fibroblast elastase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P08473

Immunogen:Peptide sequence around aa.6~10(S-Q-M-D-I) derived from Human CD10.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Yandle T.G., Brennan S.O., Espiner E.A., Nicholls M.G., Richards A.M.Peptides 10:891-894(1989)
Rice G.I., Thomas D.A., Grant P.J., Turner A.J., Hooper N.M.Biochem. J. 383:45-51(2004)
Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G.J. Biol. Chem. 285:39819-39827(2010)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MME

Research Areas:Cancer;Immunology;Stem cells