MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody

SKU: BT-AP03627

Size:100μL

Background:The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase| and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate| and activates IkappaB kinase alpha and beta| and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Research_area:Signal transduction

Target_protein:MAP3K11

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MLK3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):93170

UniProt accession:Human: Q16584; Mouse: Q80XI6; Rat: Q66HA1

Synonyms:MLK3 ;Phospho Thr277+Ser281; Mitogen-activated protein kinase kinase kinase 11; EC 2.7.11.25; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase

GeneID:Human: 4296; Mouse: 26403; Rat: 309168