MLH1 Polyclonal Antibody

SKU: BT-AP05452

Size:100μL

Background:MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:MLH1

applications:WB, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MLH1 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):84601

UniProt accession:Human: P40692; Mouse: Q9JK91; Rat: P97679

Synonyms:MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

GeneID:Human: 4292; Mouse: 17350; Rat: 81685