MESP2 Antibody - Cat. #: CSB-PA613150ESR1HU

SKU: CSB-PA613150ESR1HU

Size :50ul

Clone Number:

Aliases:Basic helix loop helix protein MESP 2 antibody; Basic helix loop helix protein MESP2 antibody; BHLH protein MesP2 antibody; bHLHc6 antibody; Class C basic helix-loop-helix protein 6 antibody; Hypothetical class II basic helix loop helix protein MESP 2 antibody; Hypothetical class II basic helix loop helix protein MESP2 antibody; Mesoderm posterior 2 antibody; mesoderm posterior 2 homolog (mouse) antibody; Mesoderm posterior 2 homolog antibody; Mesoderm posterior protein 2 antibody; Mesp 2 antibody; MESP2 antibody; MESP2_HUMAN antibody; SCDO 2 antibody; SCDO2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q0VG99

Immunogen:Recombinant Human Mesoderm posterior protein 2 protein (218-397AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MESP2

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Developmental biology