MBD3 Antibody - Cat. #: CSB-PA693569

SKU: CSB-PA693569

Size :100ul

Clone Number:

Aliases:AI181826 antibody; AU019209 antibody; MBD 3 antibody; Mbd3 antibody; MBD3: methyl CpG binding domain protein 3 antibody; MBD3_HUMAN antibody; Methyl CpG binding domain protein 3 antibody; Methyl CpG binding protein MBD3 antibody; Methyl-CpG-binding domain protein 3 antibody; Methyl-CpG-binding protein MBD3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95983

Immunogen:Synthesized peptide derived from C-terminal of Human MBD3.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.

Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).
Grimwood J., Nature 428:529-535(2004).
Tatematsu K., Genes Cells 5:677-688(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MBD3

Research Areas:Epigenetics and Nuclear Signaling