MBD3 Antibody - Cat. #: CSB-PA013532LA01HU

SKU: CSB-PA013532LA01HU

Size :50ug

Clone Number:

Aliases:AI181826 antibody; AU019209 antibody; MBD 3 antibody; Mbd3 antibody; MBD3: methyl CpG binding domain protein 3 antibody; MBD3_HUMAN antibody; Methyl CpG binding domain protein 3 antibody; Methyl CpG binding protein MBD3 antibody; Methyl-CpG-binding domain protein 3 antibody; Methyl-CpG-binding protein MBD3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95983

Immunogen:Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background:Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MBD3

Research Areas:Epigenetics and Nuclear Signaling